Rukeia El-Athman works as a research assistant in the eScience group. She studied Bioinformatics at the Freie Universität Berlin, followed by a PhD at the Institute for Theoretical Biology of the Humboldt Universität zu Berlin and the Charité – Universitätsmedizin Berlin. In her thesis, she investigated the relationship between the mammalian circadian clock and cancer progression with a focus on potentially temporally regulated alternative splicing. She received her PhD in 2020 from Freie Universität Berlin. Having joined at BAM in February 2021, she currently works in the BAM Data Store project where she is responsible for introducing a central data management framework and electronical lab notebook for a diverse set of material science and engineering groups. She is interested in different aspects of data science, from statistical analysis to research data management. She also loves coding in R, especially for large-scale data analysis and visualization.
- El-Athman R. “Computational analysis of circadian splicing events in human cancer cell lines and mammalian tissues”. PhD thesis. Freie Universität Berlin, 2020. url: http://dx.doi.org/10.17169/refubium-28101
- Müge Y, El-Athman R, Ouk K, Priller J, Relógio A. Analysis of the circadian regulation of cancer hallmarks by a cross-platform study of colorectal cancer time-series data reveals an association with genes involved in Huntington's Disease. Cancers. 2020, 12(4), 963; doi: 10.3390/cancers12040963
- El-Athman R, Knezevic D, Fuhr L, Relógio A. A computational analysis of alternative splicing across mammalian tissues reveals circadian and ultradian rhythms in splicing events. Int J Mol Sci. 2019 Aug 15;20(16). pii: E3977. doi: 10.3390/ijms20163977.
- Fuhr L, Abreu M, Carbone A, El-Athman R, Bianchi F, Laukkanen MO, Mazzoccoli G, Relógio A. The interplay between colon cancer cells and tumour-associated stromal cells impacts the biological block and enhances malignant phenotypes. Cancers. 2019 Jul 15;11(7). pii: E988. doi: 10.3390/cancers11070988.
- El-Athman R, Fuhr L, Relógio A. A systems-level analysis reveals circadian regulation of splicing in colorectal cancer. EBioMedicine. 2018 Jul;33:68-81. doi: 10.1016/j.ebiom.2018.06.012. Epub 2018 Jun 21.
- Fuhr L, El-Athman R, Scrima R, Cela O, Carbone A, Knoop H, Li Y, Hoffmann K, Laukkanen MO, Corcione F, Steuer R, Meyer TF, Mazzoccoli G, Capitanio N, Relógio A. The circadian clock regulates metabolic phenotype rewiring via HKDC1 and modulates tumor progression and drug response in colorectal cancer. EBioMedicine. 2018 Jul;33:105-121. doi: 10.1016/j.ebiom.2018.07.002. Epub 2018 Jul 10.
- El-Athman R, Relógio A. Escaping circadian regulation: An emerging hallmark of cancer? Cell Syst. 2018 Mar 28;6(3):266-267. doi: 10.1016/j.cels.2018.03.006.
- El-Athman R*, Genov NN*, Mazuch J*, Zhang K, Yu Y, Fuhr L, Abreu M, Li Y, Wallach T, Kramer A, Schmitt CA, Relógio A. The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity. PLoS Biol. 2017 Dec 7;15(12):e2002940. doi: 10.1371/journal.pbio.2002940. eCollection 2017 Dec. *These authors contributed equally.
- Milatz S, Piontek J, Hempel C, Meoli L, Grohe C, Fromm A, Lee IM, El-Athman R, Günzel D. Tight junction strand formation by claudin-10 isoforms and claudin-10a/-10b chimeras. Ann N Y Acad Sci. 2017 Oct;1405(1):102-115. doi: 10.1111/nyas.13393. Epub 2017 Jun 20.